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The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness

Cell surface glucose regulated protein 78 (GRP78), an endoplasmic reticulum (ER) chaperone, was suggested to be a cancer stem cell marker, but the influence of this molecule on cancer stemness is poorly characterized. In this study, we developed a mass spectrometry platform to detect the endogenous...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Chen, Hsin-Ying, Chang, Joseph Tung-Chieh, Chien, Kun-Yi, Lee, Yun-Shien, You, Guo-Rung, Cheng, Ann-Joy
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765009/
https://ncbi.nlm.nih.gov/pubmed/29323121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14604-5
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