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Sequential forward and reverse transport of the Na(+) Ca(2+) exchanger generates Ca(2+) oscillations within mitochondria
Mitochondrial Ca(2+) homoeostasis regulates aerobic metabolism and cell survival. Ca(2+) flux into mitochondria is mediated by the mitochondrial calcium uniporter (MCU) channel whereas Ca(2+) export is often through an electrogenic Na(+)–Ca(2+) exchanger. Here, we report remarkable functional versat...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5765001/ https://ncbi.nlm.nih.gov/pubmed/29323106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02638-2 |
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