Mouse Antibody of IgM Class is Prone to Non-Enzymatic Cleavage between CH1 and CH2 Domains

IgM is a multivalent antibody which evolved as a first line defense of adaptive immunity. It consists of heavy and light chains assembled into a complex oligomer. In mouse serum there are two forms of IgM, a full-length and a truncated one. The latter contains μ’ chain, which lacks a variable region...

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Publicat a:Sci Rep
Autors principals: Klaus, Tomasz, Stalińska, Krystyna, Czaplicki, Dominik, Mak, Paweł, Skupien-Rabian, Bozena, Kedracka-Krok, Sylwia, Wiatrowska, Karolina, Bzowska, Monika, Machula, Monika, Bereta, Joanna
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764968/
https://ncbi.nlm.nih.gov/pubmed/29323348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19003-4
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