Characterization of the biosynthetic gene cluster for cryptic phthoxazolin A in Streptomyces avermitilis

Phthoxazolin A, an oxazole-containing polyketide, has a broad spectrum of anti-oomycete activity and herbicidal activity. We recently identified phthoxazolin A as a cryptic metabolite of Streptomyces avermitilis that produces the important anthelmintic agent avermectin. Even though genome data of S....

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Veröffentlicht in:PLoS One
Hauptverfasser: Suroto, Dian Anggraini, Kitani, Shigeru, Arai, Masayoshi, Ikeda, Haruo, Nihira, Takuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764310/
https://ncbi.nlm.nih.gov/pubmed/29324854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190973
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