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Molecular Docking: From Lock and Key to Combination Lock

Accurate modeling of protein ligand binding is an important step in structure-based drug design, is a useful starting point for finding new lead compounds or drug candidates. The ‘Lock and Key’ concept of protein-ligand binding has dominated descriptions of these interactions, and has been effective...

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Pubblicato in:J Mol Med Clin Appl
Autori principali: Tripathi, Ashutosh, Bankaitis, Vytas A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764188/
https://ncbi.nlm.nih.gov/pubmed/29333532
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