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Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine
Osteogenesis imperfecta (OI) is a disease caused by defects in type I collagen production that results in brittle bones. While the pathology is mainly caused by defects in the osteoblast lineage, there is also elevated bone resorption by osteoclasts resulting in high bone turnover in severe forms of...
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| Publié dans: | Bone |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764163/ https://ncbi.nlm.nih.gov/pubmed/28600151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.06.004 |
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