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Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine

Osteogenesis imperfecta (OI) is a disease caused by defects in type I collagen production that results in brittle bones. While the pathology is mainly caused by defects in the osteoblast lineage, there is also elevated bone resorption by osteoclasts resulting in high bone turnover in severe forms of...

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Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Matthews, Brya G, Roeder, Emilie, Wang, Xi, Aguila, Hector Leonardo, Lee, S. Kyeong, Grcevic, Danka, Kalajzic, Ivo
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764163/
https://ncbi.nlm.nih.gov/pubmed/28600151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.06.004
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