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Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine

Osteogenesis imperfecta (OI) is a disease caused by defects in type I collagen production that results in brittle bones. While the pathology is mainly caused by defects in the osteoblast lineage, there is also elevated bone resorption by osteoclasts resulting in high bone turnover in severe forms of...

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Bibliografske podrobnosti
izdano v:Bone
Main Authors: Matthews, Brya G, Roeder, Emilie, Wang, Xi, Aguila, Hector Leonardo, Lee, S. Kyeong, Grcevic, Danka, Kalajzic, Ivo
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764163/
https://ncbi.nlm.nih.gov/pubmed/28600151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.06.004
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