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Left-right patterning: breaking symmetry to asymmetric morphogenesis
Vertebrates exhibit striking left-right (L-R) asymmetries in the structure and position of the internal organs. Symmetry is broken by motile cilia-generated asymmetric fluid flow, resulting in a signaling cascade — the Nodal-Pitx2 pathway — being robustly established within mesodermal tissue on the...
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| Publicado no: | Trends Genet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764106/ https://ncbi.nlm.nih.gov/pubmed/28720483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.06.004 |
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