Dengue virus infection-enhancement activity in neutralizing antibodies of healthy adults before dengue season as determined by using FcγR-expressing cells

BACKGROUND: Antibodies are critical responses to protect the host from dengue virus(DENV) infection. Antibodies target DENV by two pathologic mechanisms: virus neutralization and infection enhancement. In dengue patients, the absence of neutralizing activity in the presence of FcγR implies that infe...

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Veröffentlicht in:BMC Infect Dis
Hauptverfasser: Ly, Minh Huong Phu, Moi, Meng Ling, Vu, Thi Bich Hau, Tun, Mya Myat Ngwe, Saunders, Todd, Nguyen, Cam Nhat, Nguyen, Anh Kieu Thi, Nguyen, Hung Manh, Dao, Than Huu, Pham, Do Quyen, Nguyen, Thi Thu Thuy, Le, Thi Quynh Mai, Hasebe, Futoshi, Morita, Kouichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763606/
https://ncbi.nlm.nih.gov/pubmed/29321001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-017-2894-7
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