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Antimicrobial Peptide Combined with BMP2-Modified Mesenchymal Stem Cells Promotes Calvarial Repair in an Osteolytic Model

Repair and regeneration of inflammation-induced bone loss remains a clinical challenge. LL37, an antimicrobial peptide, plays critical roles in cell migration, cytokine production, apoptosis, and angiogenesis. Migration of stem cells to the affected site and promotion of vascularization are essentia...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Liu, Zunpeng, Yuan, Xue, Liu, Min, Fernandes, Gabriela, Zhang, Yejia, Yang, Shuting, Ionita, Ciprian N., Yang, Shuying
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762982/
https://ncbi.nlm.nih.gov/pubmed/28988712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.09.011
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