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Screening primary racemic amines for enantioseparation by derivatized polysaccharide and cyclofructan columns()

It is a challenge to separate the enantiomers of native chiral amines prone to deleterious silanol interactions. A set of 39 underivatized chiral primary amines was screened for enantiomeric separation. Seven recently introduced commercial chiral columns were tested. They included six polysaccharide...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Lim, Yeeun, Breitbach, Zachary S., Armstrong, Daniel W., Berthod, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762930/
https://ncbi.nlm.nih.gov/pubmed/29404003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.07.003
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