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Domain swapping and SMYD1 interactions with the PWWP domain of human hepatoma-derived growth factor

The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Li-Ying, Huang, Yen-Chieh, Huang, Shih-Tsung, Hsieh, Yin-Cheng, Guan, Hong-Hsiang, Chen, Nai-Chi, Chuankhayan, Phimonphan, Yoshimura, Masato, Tai, Ming-Hong, Chen, Chun-Jung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762634/
https://ncbi.nlm.nih.gov/pubmed/29321480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18510-8
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