The potential mechanism of extracellular high mobility group box-1 protein mediated p53 expression in immune dysfunction of T lymphocytes

In the present study, we examined the activity of p53 protein in Jurkat cells treated with high mobility group box-1 protein (HMGB1), thereafter we investigated the mechanism of extracellular HMGB1 mediated p53 expression in immune dysfunction of T lymphocytes. mRNA expression of p53, mdm2, and p21...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Luan, Ying-Yi, Jia, Min, Zhang, Hui, Zhu, Fu-Jun, Dong, Ning, Feng, Yong-Wen, Wu, Ming, Tong, Ya-Lin, Yao, Yong-Ming
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762565/
https://ncbi.nlm.nih.gov/pubmed/29348880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22913
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