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Comprehensive analysis of mRNA-lncRNA co-expression profile revealing crucial role of imprinted gene cluster DLK1-MEG3 in chordoma

Chordoma is a rare bone tumor with high recurrence rate, but the mechanism of its development is unclear. Long non-coding RNAs(lncRNAs) are recently revealed to be regulators in a variety of biological processed by targeting on mRNA transcription. Their expression profile and function in chordoma ha...

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Pubblicato in:Oncotarget
Autori principali: Chen, Hao, Zhang, Kai, Lu, Jian, Wu, Guizhong, Yang, Huilin, Chen, Kangwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762536/
https://ncbi.nlm.nih.gov/pubmed/29348851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22616
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