Novel indazole-based small compounds enhance TRAIL-induced apoptosis by inhibiting the MKK7-TIPRL interaction in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most malignant tumors. Although various treatments, such as surgery and chemotherapy, have been developed, a novel alternative therapeutic approach for HCC therapy is urgently needed. Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a pr...

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發表在:Oncotarget
Main Authors: Yoon, Ji-Yong, Lee, Jeong-Ju, Gu, Sujin, Jung, Myoung Eun, Cho, Hyun-Soo, Lim, Jung Hwa, Jun, Soo Young, Ahn, Jun-Ho, Min, Ju-Sik, Choi, Min-Hyuk, Jeon, Su-Jin, Lee, Yong-Jae, Go, Areum, Heo, Yun-Jeong, Jung, Cho-Rok, Choi, Gildon, Lee, Kwangho, Jeon, Moon-Kook, Kim, Nam-Soon
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762535/
https://ncbi.nlm.nih.gov/pubmed/29348850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22614
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