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Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma—an aggressive and fatal disease

NUT midline carcinoma (NMC) is a rare and aggressive cancer, with survival typically less than seven months, that can arise in people of any age. Genetically, NMC is defined by the chromosomal fusion of NUTM1 with a chromatin-binding partner, typically the bromodomain-containing protein BRD4. Howeve...

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Foilsithe in:Oncotarget
Main Authors: Stirnweiss, Anja, Oommen, Joyce, Kotecha, Rishi S., Kees, Ursula R., Beesley, Alex H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762512/
https://ncbi.nlm.nih.gov/pubmed/29348827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22862
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