Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts

The invasion of activated fibroblasts is a key mechanism of tissue fibrosis pathology. The recognition and uptake of apoptotic cells can induce the anti-fibrogenic programming of macrophages. We demonstrate that after interacting with apoptotic cells, macrophages secrete bioactive molecules that ant...

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Udgivet i:Oncotarget
Main Authors: Kim, Yong-Bae, Yoon, Young-So, Choi, Youn-Hee, Park, Eun-Mi, Kang, Jihee Lee
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762511/
https://ncbi.nlm.nih.gov/pubmed/29348826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22737
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