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Study and ICH validation of a reverse-phase liquid chromatographic method for the quantification of the intact monoclonal antibody cetuximab()

Cetuximab (CTX) is a potent chimeric mouse/human monoclonal antibody (mAb) approved worldwide for treatment of metastatic colorectal cancer. Among the various biological and physical analyses performed for full study on this biopharmaceutic, the determination of the concentration preparations throug...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Martínez-Ortega, Antonio, Herrera, Agustín, Salmerón-García, Antonio, Cabeza, José, Cuadros-Rodríguez, Luis, Navas, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762446/
https://ncbi.nlm.nih.gov/pubmed/29403971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2015.11.007
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