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Integrating gene and lncRNA expression to infer subpathway activity for tumor analyses

LncRNAs acting as miRNA sponges to indirectly regulate mRNAs is a novel layer of gene regulation, therefore, it is necessary to integrate lncRNA and gene levels for interpreting tumor biological mechanism. In this study, we developed a lncRNA-gene integrated strategy to infer functional activities f...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Zhang, Chunlong, Xu, Yanjun, Yang, Haixiu, Xu, Yingqi, Dong, Qun, Liu, Siyao, Wu, Tan, Zhang, Yunpeng
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762333/
https://ncbi.nlm.nih.gov/pubmed/29340065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22811
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