Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations()

Benidipine hydrochloride, used as an antihypertensive agent and long-acting calcium antagonist, is synthesized for commercial use as a drug substance in highly pure form. During the synthetic process development studies of benidipine, process related impurities were detected. These impurities were i...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Bellur Atici, Esen, Karlığa, Bekir
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762216/
https://ncbi.nlm.nih.gov/pubmed/29403939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2015.02.001
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