AZP-531, an unacylated ghrelin analog, improves food-related behavior in patients with Prader-Willi syndrome: A randomized placebo-controlled trial

CONTEXT AND OBJECTIVE: Prader-Willi syndrome (PWS) is characterized by early-onset hyperphagia and increased circulating levels of the orexigenic Acylated Ghrelin (AG) hormone with a relative deficit of Unacylated Ghrelin (UAG). AZP-531, a first-in-class UAG analog, was shown to inhibit the orexigen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Allas, Soraya, Caixàs, Assumpta, Poitou, Christine, Coupaye, Muriel, Thuilleaux, Denise, Lorenzini, Françoise, Diene, Gwenaëlle, Crinò, Antonino, Illouz, Frédéric, Grugni, Graziano, Potvin, Diane, Bocchini, Sarah, Delale, Thomas, Abribat, Thierry, Tauber, Maithé
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761957/
https://ncbi.nlm.nih.gov/pubmed/29320575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190849
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