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Characterization of the naive murine antibody repertoire using unamplified high-throughput sequencing
Antibody specificity and diversity are generated through the enzymatic splicing of genomic gene segments within each B cell. Antibodies are heterodimers of heavy- and light-chains encoded on separate loci. We studied the antibody repertoire from pooled, splenic tissue of unimmunized, adult female C5...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761896/ https://ncbi.nlm.nih.gov/pubmed/29320559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190982 |
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