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Brain structural changes in cynomolgus monkeys administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A longitudinal voxel-based morphometry and diffusion tensor imaging study

In animal models of Parkinson's disease (PD), 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is one of the most widely used agents that damages the nigrostriatal dopaminergic pathway. However, brain structural changes in response to MPTP remain unclear. This study aimed to investigate in v...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jeong, Hyeonseok S., Lee, Sang-Rae, Kim, Jieun E., Lyoo, In Kyoon, Yoon, Sujung, Namgung, Eun, Chang, Kyu-Tae, Kim, Bom Sahn, Yang, Sejung, Im, Jooyeon J., Jeon, Saerom, Kang, Ilhyang, Ma, Jiyoung, Chung, Yong-An, Lim, Soo Mee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761839/
https://ncbi.nlm.nih.gov/pubmed/29320500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189804
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