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Agonist OX40 immunotherapy improves survival in glioma-bearing mice and is complementary with vaccination with irradiated GM-CSF–expressing tumor cells

BACKGROUND: Glioma immunotherapy is an active area of clinical investigation. Glioma-associated immunosuppression remains an obstacle to efficacious immunotherapy, and combination approaches are likely necessary for durable success. OX40 is a member of the tumor necrosis factor receptor superfamily...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Jahan, Nusrat, Talat, Hammad, Curry, William T
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761505/
https://ncbi.nlm.nih.gov/pubmed/29016879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox125
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