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CaMKIIα Mediates the Effect of IL-17 To Promote Ongoing Spontaneous and Evoked Pain in Multiple Sclerosis

Pain is a common and severe symptom in multiple sclerosis (MS), a chronic inflammatory and demyelinating disease of the CNS. The neurobiological mechanism underlying MS pain is poorly understood. In this study, we investigated the role of Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) in d...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hu, Xiaoyu, Huang, Fang, Wang, Zaijie Jim
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761434/
https://ncbi.nlm.nih.gov/pubmed/29146590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2666-17.2017
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