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Simultaneous determination of ezetimibe and simvastatin in rat plasma by stable-isotope dilution LC-ESI–MS/MS and its application to a pharmacokinetic study
A simple, sensitive and specific liquid chromatography–tandem mass spectrometry method was developed for simultaneous quantification of ezetimibe and simvastatin in rat plasma. The deuterium isotopes: ezetimibe d(4) and simvastatin d(6) were used as internal standards for ezetimibe and simvastatin,...
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| Publicado no: | J Pharm Anal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Xi'an Jiaotong University
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761217/ https://ncbi.nlm.nih.gov/pubmed/29403892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2013.08.002 |
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