Simultaneous determination of human plasma protein binding of bioactive flavonoids in Polygonum orientale by equilibrium dialysis combined with UPLC–MS/MS

A simple and selective ultra performance liquid chromatography–electrospray ionization tandem mass spectrometry (UPLC–ESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four bioactive flavonoids (such as orientin and vitexin) in Polygonum orientale. Protein p...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Huang, Yong, Chen, Hui, He, Feng, Zhang, Zhi-Rong, Zheng, Lin, Liu, Yue, Lan, Yan-Yu, Liao, Shang-Gao, Li, Yong-Jun, Wang, Yong-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761012/
https://ncbi.nlm.nih.gov/pubmed/29403842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2013.04.001
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