LC–MS/MS determination and pharmacokinetic study of bergenin, the main bioactive component of Bergenia purpurascens after oral administration in rats

Bergenin, a C-glucoside of 4-O-methyl gallic acid from Bergenia purpurascens, is a naturally antitussive and expectorant agent. A rapid and sensitive liquid chromatography tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the determination of the active component—bergen...

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Bibliografiske detaljer
Udgivet i:J Pharm Anal
Main Authors: Li, Bao-Hong, Wu, Jin-Dong, Li, Xiang-Lu
Format: Artigo
Sprog:Inglês
Udgivet: Xi'an Jiaotong University 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760982/
https://ncbi.nlm.nih.gov/pubmed/29403822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2013.01.005
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