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Preparation of gastro-resistant pellets containing chitosan microspheres for improvement of oral didanosine bioavailability

The purpose of this work was to introduce a new concept of coated pellets containing chitosan microspheres loaded with didadosine for oral administration, aiming at reducing the frequency of administration and improving the bioavailability by a suitable release profile. Chitosan microspheres were pr...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Severino, Patrícia, de Oliveira, George G.G., Ferraz, Humberto G., Souto, Eliana B., Santana, Maria H.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760906/
https://ncbi.nlm.nih.gov/pubmed/29403741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2012.02.005
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