Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines

Toxoplasma gondii is a major source of congenital disease worldwide, but the cellular and molecular factors associated with its vertical transmission are largely unknown. In humans, the placenta forms the key interface between the maternal and fetal compartments and forms the primary barrier that re...

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Udgivet i:mBio
Main Authors: Ander, Stephanie E., Rudzki, Elizabeth N., Arora, Nitin, Sadovsky, Yoel, Coyne, Carolyn B., Boyle, Jon P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760739/
https://ncbi.nlm.nih.gov/pubmed/29317509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01678-17
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