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Engineering human pluripotent stem cells into a functional skeletal muscle tissue
The generation of functional skeletal muscle tissues from human pluripotent stem cells (hPSCs) has not been reported. Here, we derive induced myogenic progenitor cells (iMPCs) via transient overexpression of Pax7 in paraxial mesoderm cells differentiated from hPSCs. In 2D culture, iMPCs readily diff...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5760720/ https://ncbi.nlm.nih.gov/pubmed/29317646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02636-4 |
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