Mechanism and structural diversity of exoribonuclease-resistant RNA structures in flaviviral RNAs

Flaviviruses such as Yellow fever, Dengue, West Nile, and Zika generate disease-linked viral noncoding RNAs called subgenomic flavivirus RNAs. Subgenomic flavivirus RNAs result when the 5′–3′ progression of cellular exoribonuclease Xrn1 is blocked by RNA elements called Xrn1-resistant RNAs located w...

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Publicado no:Nat Commun
Main Authors: MacFadden, Andrea, O’Donoghue, Zoe, Silva, Patricia A. G. C., Chapman, Erich G., Olsthoorn, René C., Sterken, Mark G., Pijlman, Gorben P., Bredenbeek, Peter J., Kieft, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760640/
https://ncbi.nlm.nih.gov/pubmed/29317714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02604-y
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