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TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve activity. In wildtype (TRPV1(+/+)) and TRPV1 knockou...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Grundy, Luke, Daly, Donna M., Chapple, Christopher, Grundy, David, Chess-Williams, Russ
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760578/
https://ncbi.nlm.nih.gov/pubmed/29317663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18136-w
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