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TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder

Both TRPV1 and P2X receptors present on bladder sensory nerve fibres have been implicated in mechanosensation during bladder filling. The aim of this study was to determine possible interactions between these receptors in modulating afferent nerve activity. In wildtype (TRPV1(+/+)) and TRPV1 knockou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grundy, Luke, Daly, Donna M., Chapple, Christopher, Grundy, David, Chess-Williams, Russ
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760578/
https://ncbi.nlm.nih.gov/pubmed/29317663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18136-w
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