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CCR2 is not required for Ly6C(hi) monocyte egress from the bone marrow, but is necessary for migration within the brain in La Crosse Virus encephalitis
Inflammatory monocyte (iMOs) recruitment to the brain is a hallmark of many neurological diseases. Prior to entering the brain, iMOs must first egress into the blood from the bone marrow through mechanism which for known encephalitic viruses is CCR2-dependent. Here, we show that during La Crosse Vir...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5760479/ https://ncbi.nlm.nih.gov/pubmed/29246952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701230 |
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