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Estrogen receptor alpha (ERα) signaling exacerbates immune-mediated nephropathies through alteration of metabolic activity()
Glomerulonephritis (GN) is one of the most serious manifestations of systemic lupus erythematous (SLE). Because SLE is at least ten times more common in women, a role for estrogens in disease pathogenesis has long been suspected. Estrogen receptor alpha (ERα) is highly expressed in renal tissue. We...
Enregistré dans:
| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5760359/ https://ncbi.nlm.nih.gov/pubmed/29237779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700770 |
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