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Naïve CD4(+) T cells carrying a TLR2 agonist overcome TGF–β-mediated tumor immune evasion
Toll-like receptor (TLR) agonists are effective at treating superficial cancerous lesions but their use internally for other types of tumors remains challenging due to toxicity. Here we report murine and human naïve CD4(+) T cells spontaneously sequester the TLR2 agonist Pam(3)Cys(4) (CD4(+) T(Pam3)...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5760318/ https://ncbi.nlm.nih.gov/pubmed/29212908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700396 |
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