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Exercise Intolerance in HFpEF: Diagnosing and Ranking its Causes Using Personalized O(2) Pathway Analysis

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with a pressing shortage of therapies. Exercise intolerance is a cardinal symptom of HFpEF, yet its pathophysiology remains uncertain. METHODS: We investigated the mechanism of exercise intolerance in each of 134...

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Vydáno v:Circulation
Hlavní autoři: Houstis, Nicholas E, Eisman, Aaron S, Pappagianopoulos, Paul P, Wooster, Luke, Bailey, Cole S, Wagner, Peter D, Lewis, Gregory D
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760316/
https://ncbi.nlm.nih.gov/pubmed/28993402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.029058
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