MAC-sparing effect of nitrous oxide in sevoflurane anesthetized sheep and its reversal with systemic atipamezole administration

INTRODUCTION: Nitrous oxide (N(2)O) is an anesthetic gas with antinociceptive properties and reduces the minimum alveolar concentration (MAC) for volatile anesthetic agents, potentially through mechanisms involving central alpha(2)-adrenoceptors. We hypothesized that 70% N(2)O in the inspired gas wi...

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Publicat a:PLoS One
Autors principals: Duffee, Lauren, Columbano, Nicolò, Scanu, Antonio, Melosu, Valentino, Careddu, Giovanni Mario, Sotgiu, Giovanni, Driessen, Bernd
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760021/
https://ncbi.nlm.nih.gov/pubmed/29315308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190167
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