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Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway

BACKGROUND: Breast cancer is one of the most commonly diagnosed invasive cancers among women around the world. Among several subtypes, triple negative breast cancer (TNBC) is highly aggressive and chemoresistant. Treatment of TNBC patients has been challenging due to heterogeneity and devoid of well...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kumar, Dhiraj, Haldar, Saikat, Gorain, Mahadeo, Kumar, Santosh, Mulani, Fayaj A., Yadav, Amit S., Miele, Lucio, Thulasiram, Hirekodathakallu V., Kundu, Gopal C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759831/
https://ncbi.nlm.nih.gov/pubmed/29310608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3876-2
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