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Covalent modification of biological targets with natural products through Paal–Knorr pyrrole formation

Natural products and endogenous metabolites engage specific targets within tissues and cells through complex mechanisms. This review examines the extent to which natural systems have adopted the Paal–Knorr reaction to engage nucleophilic amine groups within biological targets. Current understanding...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Prod Rep
Prif Awduron: Kornienko, Alexander, La Clair, James J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759776/
https://ncbi.nlm.nih.gov/pubmed/28808718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7np00024c
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