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Structural basis of MsbA-mediated lipopolysaccharide transport

Lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria is critical for their cell envelope assembly. LPS synthesized in the cytoplasmic leaflet of the inner membrane is flipped to the periplasmic leaflet by MsbA, an ATP-binding cassette transporter. Despite substantial efforts, the...

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Bibliografische gegevens
Gepubliceerd in:Nature
Hoofdauteurs: Mi, Wei, Li, Yanyan, Yoon, Sung Hwan, Ernst, Robert K., Walz, Thomas, Liao, Maofu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759761/
https://ncbi.nlm.nih.gov/pubmed/28869968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23649
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