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Structural basis of MsbA-mediated lipopolysaccharide transport
Lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria is critical for their cell envelope assembly. LPS synthesized in the cytoplasmic leaflet of the inner membrane is flipped to the periplasmic leaflet by MsbA, an ATP-binding cassette transporter. Despite substantial efforts, the...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5759761/ https://ncbi.nlm.nih.gov/pubmed/28869968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23649 |
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