Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer’s Disease

IMPORTANCE: It is unclear if female carriers of the Apolipoprotein E (APOE) ε4 allele are at greater risk of developing Alzheimer’s disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been established. OBJECTIVE: To determine how sex and APOE...

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Vydáno v:JAMA Neurol
Hlavní autoři: Neu, Scott C., Pa, Judy, Kukull, Walter, Beekly, Duane, Kuzma, Amanda, Gangadharan, Prabhakaran, Wang, Li-San, Romero, Klaus, Arneric, Stephen P., Redolfi, Alberto, Orlandi, Daniele, Frisoni, Giovanni B., Au, Rhoda, Devine, Sherral, Auerbach, Sanford, Espinosa, Ana, Boada, Mercè, Ruiz, Agustín, Johnson, Sterling C., Koscik, Rebecca, Wang, Jiun-Jie, Hsu, Wen-Chuin, Chen, Yao-Liang, Toga, Arthur W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759346/
https://ncbi.nlm.nih.gov/pubmed/28846757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.2188
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