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Influences of Anlotinib on Cytochrome P450 Enzymes in Rats Using a Cocktail Method
The present study aimed to investigate the effect of anlotinib (AL3818) on pharmacokinetics of cytochrome P450 (CYP) enzymes (CYP1A2, CYP2C6, CYP2D1, CYP2D2, and CYP3A1/2) by using five cocktail probe drugs in vivo. After pretreatment for 7 days with anlotinib (treatment group) or saline (control gr...
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| Vydáno v: | Biomed Res Int |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Hindawi
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758843/ https://ncbi.nlm.nih.gov/pubmed/29441353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3619723 |
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