Hepatic dysfunction and thrombocytopenia induced by excess sFlt1 in mice lacking endothelial nitric oxide synthase

Liver dysfunction is a major problem in patients with severe preeclampsia (PE), hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome, or in patients receiving anti-vascular endothelial growth factor (VEGF) therapy. Excessive soluble fms-like tyrosine kinase 1 (sFlt1) that antag...

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Foilsithe in:Sci Rep
Main Authors: Oe, Yuji, Ko, Mieko, Fushima, Tomofumi, Sato, Emiko, Karumanchi, S. Ananth, Sato, Hiroshi, Sugawara, Junichi, Ito, Sadayoshi, Takahashi, Nobuyuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758763/
https://ncbi.nlm.nih.gov/pubmed/29311569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18260-7
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