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WNK1 is required for proliferation induced by hypotonic challenge in rat vascular smooth muscle cells
Hypotonic challenge evoked vascular cell proliferation through activation of volume-regulated Cl(−) channel (VRCC), leading to a decrease in the intracellular Cl(−) concentration ([Cl(−)](i)). We hypothesize that the decrease in [Cl(−)](i) may activate one or several Cl(−)-sensitive kinases, resulti...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758668/ https://ncbi.nlm.nih.gov/pubmed/28770829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.56 |
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