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Linked cycles of oxidative decarboxylation of glyoxylate as protometabolic analogs of the citric acid cycle

The development of metabolic approaches towards understanding the origins of life, which have focused mainly on the citric acid (TCA) cycle, have languished—primarily due to a lack of experimentally demonstrable and sustainable cycle(s) of reactions. We show here the existence of a protometabolic an...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Springsteen, Greg, Yerabolu, Jayasudhan Reddy, Nelson, Julia, Rhea, Chandler Joel, Krishnamurthy, Ramanarayanan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758577/
https://ncbi.nlm.nih.gov/pubmed/29311556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02591-0
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