Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis

Lipid metabolism is drastically dysregulated in amyotrophic lateral sclerosis and impacts prognosis of patients. Animal models recapitulate alterations in the energy metabolism, including hypermetabolism and severe loss of adipose tissue. To gain insight into the molecular mechanisms underlying dise...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Henriques, Alexandre, Croixmarie, Vincent, Bouscary, Alexandra, Mosbach, Althéa, Keime, Céline, Boursier-Neyret, Claire, Walter, Bernard, Spedding, Michael, Loeffler, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758557/
https://ncbi.nlm.nih.gov/pubmed/29354030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00433
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