Ets-2 Acts As a Transcriptional Repressor of the Human Immunodeficiency Virus Type 1 through Binding to a Repressor–Activator Target Sequence of 5′-LTR

HIV-1 is transcriptionally active in activated T helper (Th)-cells and inactive in naive or resting memory Th-cells. Ets-2 is a preinduction transcriptional repressor of the IL-2 gene in naive Th-cells and a candidate transcriptional repressor of HIV-1 in the same cells, because the −279 to −250 ups...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Panagoulias, Ioannis, Karagiannis, Fotios, Aggeletopoulou, Ioanna, Georgakopoulos, Tassos, Argyropoulos, Christos P., Akinosoglou, Karolina, Gogos, Charalambos, Skoutelis, Athanasios, Mouzaki, Athanasia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758550/
https://ncbi.nlm.nih.gov/pubmed/29354130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01924
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