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Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice
Obesity places an enormous medical and economic burden on society. The principal driver appears to be central leptin resistance with hyperleptinemia. Accordingly, a compound that reverses or prevents leptin resistance should promote weight normalisation and improve glucose homeostasis. The protease...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5758523/ https://ncbi.nlm.nih.gov/pubmed/29311632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18388-6 |
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