Radiogenomic analysis of hypoxia pathway is predictive of overall survival in Glioblastoma

Hypoxia, a characteristic trait of Glioblastoma (GBM), is known to cause resistance to chemo-radiation treatment and is linked with poor survival. There is hence an urgent need to non-invasively characterize tumor hypoxia to improve GBM management. We hypothesized that (a) radiomic texture descripto...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Beig, Niha, Patel, Jay, Prasanna, Prateek, Hill, Virginia, Gupta, Amit, Correa, Ramon, Bera, Kaustav, Singh, Salendra, Partovi, Sasan, Varadan, Vinay, Ahluwalia, Manmeet, Madabhushi, Anant, Tiwari, Pallavi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758516/
https://ncbi.nlm.nih.gov/pubmed/29311558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18310-0
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